Description
Product Characteristics: SENP7, SUMO1/sentrin specific peptidase 7, KIAA1707, MGC157730, SUMO1/sentrin specific protease 7, sentrin/SUMO-specific protease, sentrin/SUMO-specific protease 7
Target Information: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\, MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009]